High Dietary Advanced Glycation End Products Impair Mitochondrial and Cognitive Function
نویسندگان
چکیده
منابع مشابه
Dietary Advanced Glycation End Products and Aging
Advanced glycation end products (AGEs) are a heterogeneous, complex group of compounds that are formed when reducing sugar reacts in a non-enzymatic way with amino acids in proteins and other macromolecules. This occurs both exogenously (in food) and endogenously (in humans) with greater concentrations found in older adults. While higher AGEs occur in both healthy older adults and those with ch...
متن کاملAdvanced glycation end products
Aging is the progressive accumulation of damage to an organism over time leading to disease and death. Aging research has been very intensive in the last years aiming at characterizing the pathophysiology of aging and finding possibilities to fight age-related diseases. Various theories of aging have been proposed. In the last years advanced glycation end products (AGEs) have received particula...
متن کاملVascular Effects of Dietary Advanced Glycation End Products
Evidence has accumulated lately demonstrating that advanced glycation end products (AGEs) play an important role in the development of diabetic and cardiovascular complications as well as the development of other chronic diseases. AGEs originating from diet have a significant contribution to the AGEs body pool and therefore dietary interventions aiming at reducing AGEs load are believed to exer...
متن کاملEffect of Dietary Advanced Glycation End Products on Mouse Liver
UNLABELLED The exact pathophysiology of non-alcoholic steatohepatitis (NASH) is not known. Previous studies suggest that dietary advanced glycation end products (AGEs) can cause oxidative stress in liver. We aim to study the effects of dietary AGEs on liver health and their possible role in the pathogenesis of NASH. METHODS Two groups of mice were fed the same diet except the AGE content vari...
متن کاملAdvanced glycation end products affect growth and function of osteoblasts.
OBJECTIVES Advanced glycation end products (AGEs) have been implicated in the pathogenesis of bone-destructive disorders. Yet reports on the influence of AGEs on human osteoblasts remain lacking. The aim of the study is to investigate the influence of AGE-modified bovine serum albumin (AGE-BSA) on cell growth and expression of osteoblastic markers associated with osteogenesis and osteoclastogen...
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ژورنال
عنوان ژورنال: Journal of Alzheimer's Disease
سال: 2020
ISSN: 1387-2877,1875-8908
DOI: 10.3233/jad-191236